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Molecular dynamics studies of conformational switching hydroxyapatite binding proteins
by Andrew T Church
| Institution: | Deakin University |
|---|---|
| Department: | |
| Degree: | |
| Year: | 2017 |
| Keywords: | controlled folding; JAK1; osteocalcin; HAP binding proteins |
| Posted: | 2/1/2018 |
| Record ID: | 2151615 |
| Full text PDF: | http://hdl.handle.net/10536/DRO/DU:30103748 |
This work studied protein conformations in solution and at the inorganic interface via the use of state of the art molecular simulation techniques. Results suggested that distinct coordination of calcium may be crucial to folding in some proteins, an important observation crucial to future advancements in materials research. Advisors/Committee Members: Walsh, Tiffany, Hughes, Zak.
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