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Abstracts Chemistry
Synthesis, Characterisation, and Biological Evaluation of Novel Metal Flavonolate Complexes
by KIRRALEE JACALYNE BURKE
| Institution: | Monash University |
|---|---|
| Department: | Science |
| Degree: | |
| Year: | 2022 |
| Keywords: | Bioinorganic Chemistry; Organometallic Chemistry; Flavonols; Bismuth; Gallium; Indium |
| Posted: | 3/25/2025 |
| Record ID: | 2242440 |
| Full text PDF: | http://hdl.handle.net/10.26180/19217358.v1 |
Abstract
Flavonols are molecules of plant origin with diverse therapeutic properties. This work explored the synthesis and biological evaluation of flavonolate complexes with medicinally-relevant metals, namely: gallium, indium, and bismuth. Important structural features that determine the solubility and biological activity of the respective metal-flavonolate complexes were elucidated; providing a foundation for the rational design of effective metal-based antibacterial and anticancer agents.
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